Randomized Control Trials

Format: Videos

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Language/s: English

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Resource Link: View the Video

Target Audience: Undergraduate

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Short Description:

1/2, 40-min lecture on randomized trials by Dr R Ramakrishnan (Lecture 25) for the Central Coordinated Bioethics Programme in India.

Key Concepts addressed:

• 1-3 Association is not the same as causation
• 2-1 Comparisons are needed to identify treatment effects
• 2-2 Comparison groups should be similar
• 2-4 Comparison groups should be treated equally
• 2-5 People should not know which treatment they get

Details

1/2, 40-min lecture on randomized trials by Dr R Ramakrishnan (Lecture 25) for the Central Coordinated Bioethics Programme for India. The approximate starting points in minutes and seconds for each section of the lecture are shown below:

02:32  Hierarchy of study designs

04:30  Difference between observation and experiment

06:26  Interpretation of measures of association – chance, bias and confounding

09:20  Bias in epidemiological studies

09:45  Randomised trials

14:20  Phases of trials

19:24  Classification of Phase III trials

30:54  RCT assures comparability

32:44  Assuring methodological rigour in RCTs

35:30  Advantages of RCTs

37:28  Disadvantages of RCTs