3-4 Do treatment comparisons reflect your circumstances?

Some treatment comparisons are designed to find out if a treatment can work under ideal circumstances, for example with people who are most likely to benefit, and most likely to comply, and with highly trained practitioners who deliver the treatment exactly as intended. These comparisons, which are sometimes called explanatory or efficacy studies, may not reflect what happens under usual circumstances.

Be aware that the results of studies with the aim of finding out if a treatment can work may overestimate the benefits of a treatment under more usual circumstances.

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