In this 5 min audio resource, Neeraj Bhala discusses systematic reviews and the impact of mega-trials.Key Concepts addressed:
- 2-2 Comparison groups should be similar
- 2-15 Fair comparisons with few people or outcome events can be misleading
Some of the most influential healthcare research of recent decades have been mega-trials in which thousands of patients have been randomised to different treatments. Neeraj Bhala from the home of several of these trials at the Clinical Trial Service Unit in the University of Oxford in England outlines their impact.